Table 4 Outcome measure data from placebo control group at all assessment time-points
Measures | Baseline (week 0) | Visit 4 (week2) | Visit 8 (week 4) | 4-week follow-up (week 8) | 8-week follow-up (week 12) | 12-week follow-up (week 16) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | Mean | SD | N | Mean | SD | N | Mean | SD | N | Mean | SD | N | Mean | SD | N | Mean | SD | |
SPA (peak pain–baseline pain) | ||||||||||||||||||
Pre | 10 | 2.35 | 0.94 | 8 | 0.50 | 0.76 | 7 | 0.00 | 0.16 | – | – | – | – | – | – | – | – | – |
Post | 10 | 1.35 | 1.00 | 8 | 0.63 | 0.74 | 7 | 0.57 | 1.27 | – | – | – | – | – | – | – | – | – |
Pain severity | ||||||||||||||||||
Worst | 10 | 5.30 | 2.21 | 8 | 3.87 | 2.17 | 7 | 3.00 | 2.00 | 10 | 4.40 | 2.99 | 10 | 4.30 | 2.67 | 10 | 3.70 | 2.41 |
At least | 10 | 1.70 | 1.83 | 8 | 1.13 | 1.36 | 7 | 0.14 | 0.38 | 10 | 2.40 | 3.06 | 10 | 2.30 | 2.98 | 10 | 1.80 | 3.05 |
Average | 10 | 3.80 | 1.62 | 8 | 2.25 | 1.75 | 7 | 1.29 | 1.25 | 10 | 3.40 | 2.80 | 10 | 3.20 | 2.66 | 10 | 2.70 | 2.67 |
Right now | 10 | 2.80 | 1.99 | 8 | 1.50 | 1.07 | 7 | 1.57 | 2.23 | 10 | 3.00 | 3.37 | 10 | 2.70 | 3.37 | 10 | 2.10 | 2.89 |
Index | 10 | 3.4 | 2.28 | 8 | 2.19 | 1.89 | 7 | 1.50 | 1.86 | 10 | 3.30 | 3.03 | 10 | 3.1 | 2.92 | 10 | 2.6 | 2.75 |
WOMAC | ||||||||||||||||||
Pain | 10 | 7.10 | 2.38 | 8 | 5.38 | 2.26 | 7 | 4.14 | 2.67 | 10 | 6.50 | 4.25 | 10 | 7.10 | 4.33 | 10 | 6.10 | 4.48 |
Stiffness | 10 | 3.00 | 0.94 | 8 | 3.00 | 1.51 | 7 | 2.00 | 1.16 | 10 | 3.60 | 1.65 | 10 | 3.50 | 1.96 | 10 | 2.70 | 1.89 |
Physical Function | 10 | 25.20 | 6.96 | 8 | 21.38 | 10.03 | 7 | 10.71 | 7.85 | 10 | 23.00 | 20.13 | 10 | 24.40 | 19.12 | 10 | 19.10 | 17.84 |
Total | 10 | 35.30 | 8.98 | 8 | 29.75 | 13.01 | 7 | 16.86 | 10.72 | 10 | 33.10 | 25.00 | 10 | 35.00 | 25.07 | 10 | 27.90 | 23.81 |
GROC Function | – | – | – | 8 | 7.00 | 0.76 | 7 | 7.86 | 0.69 | 10 | 6.60 | 2.22 | 10 | 6.90 | 2.38 | 10 | 7.60 | 1.58 |
GROC Pain | – | – | – | 8 | 6.50 | 1.07 | 7 | 7.71 | 1.50 | 10 | 6.30 | 2.14 | 10 | 6.80 | 2.30 | 10 | 7.20 | 1.93 |
Satisfaction | – | – | – | 8 | 9.62 | 1.60 | 7 | 9.57 | 0.98 | 10 | 9.50 | 2.01 | 10 | 8.90 | 3.04 | 10 | 9.30 | 1.95 |
6MWT (m) | ||||||||||||||||||
Pre | 10 | 321.97 | 88.53 | 8 | 393.37 | 92.82 | 7 | 428.95 | 90.15 | – | – | – | – | – | – | – | – | – |
Post | 10 | 317.77 | 89.80 | 8 | 379.44 | 80.30 | 6 | 433.05 | 100.56 | – | – | – | – | – | – | – | – | – |
Pressure pain threshold–mean of peripatellar sites (N) | ||||||||||||||||||
Most tender knee | 10 | 51.89 | 36.27 | – | – | – | 7 | 60.29 | 25.01 | – | – | – | – | – | – | – | – | – |
Least tender knee | 10 | 52.70 | 28.57 | – | – | – | 7 | 73.98 | 62.05 | – | – | – | – | – | – | – | – | – |
Pressure pain threshold – standard site over tibialis anterior (N) | ||||||||||||||||||
Most tender knee | 10 | 38.10 | 18.87 | – | – | – | 7 | 42.64 | 12.52 | – | – | – | – | – | – | – | – | – |
Least tender knee | 10 | 40.20 | 16.10 | – | – | – | 7 | 48.50 | 18.93 | – | – | – | – | – | – | – | – | – |