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Fig. 4 | Pilot and Feasibility Studies

Fig. 4

From: Does in utero HIV exposure and the early nutritional environment influence infant development and immune outcomes? Findings from a pilot study in Pretoria, South Africa

Fig. 4

Relationships between in utero HIV exposure and attainment of GMCD neurodevelopmental milestones 1–3 months (a) and 3–5 months (b) of age. There was no detected difference in the proportion of infants who were HUU (n = 8) compared to HEU (n = 14) who attained GMCD milestones at 1–3 months of age ([p > 0.05], Fisher’s exact), and no comparisons between infants who were HUU vs. HEU were made for 3–5-month milestones met, given that only 1/10 infants who were HUU at follow-up was 3–5 months of age. All infants met milestones when comparing to the GMCD standardisation sample, except for infants who were HUU for 1–3-month receptive language, large movement and play activities milestones, and infants who were HEU for fine movement milestones at 3–5 months of age. Bar graphs are proportion (%) attaining all age-appropriate GMCD milestones. GMCD Guide for Monitoring Child Development; HUU HIV-unexposed, uninfected; HEU HIV-exposed, uninfected

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