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Fig. 3 | Pilot and Feasibility Studies

Fig. 3

From: Does in utero HIV exposure and the early nutritional environment influence infant development and immune outcomes? Findings from a pilot study in Pretoria, South Africa

Fig. 3

CCR2 expression by monocyte sub-populations within 4 days of birth and at 12 (± 4) weeks of age. Infants who were HEU (n = 32) had elevated %CCR2-positive classical monocytes (a; p = 0.01) and CCR2 expression (MFI) on intermediate monocytes at birth (e; p = 0.03) and 12 weeks (e; 0.04) compared to infants who were HUU (n = 21). Data are measured as proportion of monocyte sub-populations expressing CCR2 (%) and the average (median) levels of expression per cell (MFI) on monocyte sub-populations. Outlier box plots are quartiles, median lines and 95% confidence diamonds, *p < 0.05 [ANCOVA]. HUU HIV-unexposed, uninfected; HEU HIV-exposed, uninfected; MFI median fluorescent intensity (MFI); CI confidence interval

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