Table 5 Effects of unfractionated heparin on acute chest syndrome
Outcome | Standard of care | Unfractionated heparin | Mean difference with 95% CI |
|---|---|---|---|
Duration of hospitalization (h) | 127 ± 138 | 279 ± 268 | 152 (− 290, 594) |
73 (25, 284) | 238 (47, 595) | ||
Duration of hypoxemia (h) | 51 ± 45 | 118 ± 61 | 66 (− 42, 174) |
73 (0, 81) | 127 (47, 168) | ||
Duration of fever (h) | 0 ± 0 | 25 ± 30 | 25 (− 33, 162) |
0 (0, 0) | 20 (0, 59) | ||
Duration of leukocytosis (h) | 53 ± 25 | 118 ± 61 | 64 (− 33, 162) |
61 (25, 73) | 127 (47, 168) | ||
Duration of moderate to severe pain (h) | 89 ± 73 | 118 ± 61 | 29 (− 100, 158) |
73 (25, 168) | 127 (47, 168) | ||
Total dose of opioids (mg oral morphine equivalents) | 1167 ± 1113 | 3447 ± 4466 | 2280 (− 4651, 9211) |
1786 (317, 9900) | |||
Number of red blood cell transfusions | 4 | 5 | |
Transfer to the intensive care unit | 1 (33%) | 0 (0%) | |
Mechanical ventilation | 0 (0%) | 0 (0%) | |
Multiorgan dysfunction syndrome | 0 (0%) | 0 (0%) |