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Table 2 Patient characteristics for the surgical and radiotherapy cohorts

From: Development and validation of a follow-up methodology for a randomised controlled trial, utilising routine clinical data as an alternative to traditional designs: a pilot study to assess the feasibility of use for the BladderPath trial

 

Data quality analysis cohorts

Survival analysis cohorts

All radiotherapy

Surgical

Radical radiotherapy

Radical cystectomy

n = 525

n = 206

Chemoradiation n = 66

Radiotherapy alone n = 270

All n = 335

Number of patients (%)

Age at 1st treatment

Median (IQR)

75 (68–94)

66.5 (56–73)

75 (67–79)

76.5 (70–82)

68 (62–74)

Range

31–96

22–85

52–90

42–94

23–86

Gender

Male

380 (72.4%)

147 (71.4%)

47 (71.2%)

200 (74.1%)

248 (74.0%)

Female

144 (27.4%)

59 (28.6%)

19 (28.8%)

70 (25.9%)

87 (26.0%)

Ethnicity

White

401 (76.4%)

191 (92.7%)

53 (80.3%)

203 (75.2%)

304 (90.7%)

Asian/Asian British

18 (3.4%)

9 (4.4%)

2 (3.0%)

9 (3.3%)

17 (5.1%)

Black/Black British

5 (1.0%)

3 (1.5%)

0 (0.0%)

4 (1.5%)

1 (0.3%)

Mixed

7 (1.3%)

0 (0.0%)

2 (3.0%)

3 (1.1%)

1 (0.3%)

Other

2 (0.4%)

2 (1.0%)

1 (1.5%)

0 (0.0%)

2 (0.6%)

Unknown

91 (17.3%)

1 (0.5%)

8 (12.1%)

51 (18.9%)

10 (3%)

Charlson score

< 1

253 (48.2%)

116 (56.3%)

33 (50.0%)

125 (46.3%)

216 (64.5%)

1–5

73 (13.9%)

45 (21.8%)

14 (21.2%)

31 (11.5%)

55 (16.4%)

6–10

39 (7.4%)

23 (11.2%)

8 (12.1%)

17 (6.3%)

45 (13.4%)

11–15

21 (4.0%)

10 (4.9%)

3 (4.5%)

7 (2.6%)

12 (3.6%)

16–20

11 (2.1%)

5 (2.4%)

4 (6.1%)

5 (1.9%)

4 (1.2%)

> 20

8 (1.5%)

3 (1.5%)

0 (0.0%)

4 (1.5%)

3 (0.9%)

Unknown

119 (22.7%)

4 (1.9%)

4 (6.1%)

81 (30.0%)

0 (0.0%)

  1. Patients without a HID inpatient event have an unknown Charlson score. Due to rounding, percentages may not sum to 100%