Table 1 Participant characteristics at baseline
Characteristic | Pediatric tubes (n = 100) | Adult tubes (n = 100) |
|---|---|---|
Age, year, mean (SD) | 55 (16.7) | 57 (18.5) |
Women, n (%) | 45 (45) | 51 (51) |
Race, n (%) | ||
White | 38 (38) | 39 (39) |
Black | 36 (36) | 46 (46) |
Other | 26 (26) | 15 (15) |
ICU admission hemoglobin, g/dL | ||
Median (IQR) | 11.4 (9.3–12.7) | 11.3 (9.2–12.7) |
Mean (SD) | 11.4 (2.4) | 11.1 (2.3) |
ICU admission hemoglobin category, n (%) | ||
7–9.49 g/dL | 27 (27) | 29 (29) |
9.5–11.99 g/dL | 32 (32) | 32 (32) |
≥ 12 g/dL | 41 (41) | 39 (39) |
Time from ICU admission to randomization, h, median (IQR) | 5.3 (1.5–8) | 5.7 (2.6–8.6) |
Estimated blood volume per participant, L, median (IQR)a | 4.9 (4.2–5.6) | 4.6 (3.9–5.4) |
Chronic hemodialysis, n (%) | 12 (12) | 12 (12) |
Chronic kidney disease but no dialysis, n (%) | 13 (13) | 11 (11) |
Active malignancy, n (%) | 5 (5) | 5 (5) |
Recent history of anemia, n (%)b | 45 (45) | 47 (47) |
Charlson comorbidity index, median (IQR)c | 3.0 (2–6) | 4.0 (2–5) |
ICU admission diagnosis, n (%)d | ||
Infection | 55 (55) | 46 (46) |
Acute cardiovascular disorder | 21 (21) | 24 (24) |
Acute renal failure | 40 (40) | 31 (31) |
Metabolic disorder | 32 (32) | 36 (36) |
Non-infectious inflammatory disordere | 19 (19) | 11 (11) |
Other | 22 (22) | 31 (31) |
Invasive mechanical ventilation, n (%) | 50 (50) | 51 (51) |
APACHE II score, median (IQR)f | 22.0 (14-29) | 23.0 (16-28) |