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Table 3 Common head and neck/general complications conformed to the Clavien-Dindo classification

From: Determining the effectiveness of fibrin sealants in reducing complications in patients undergoing lateral neck dissection (DEFeND): study protocol for a randomised external pilot trial

Post-operative complicationDescription of severityClavien-Dindo grade
Neck wound infectionLocalised and superficial to platysma, e.g. stitch abscessI
Spreading cellulitis or superficial wound infection with no underlying collection treated with antibioticsII
Collection deep to platysma requiring drainage (not under GA)IIIa
Collection deep to platysma requiring drainage (under GA)IIIb
Large collection with organ and/or life-threatening sequelae (i.e. airway obstruction, severe sepsis, septic shock)IV (a or b depending on organ dysfunction)
Other surgical site infectionLocalised infection requiring topical or non-invasive treatmentI
Infection requiring treatment with antibiotics onlyII
Collection requiring drainage (not under GA)IIIa
Collection requiring drainage (under GA)IIIb
Large collection with organ and/or life-threatening sequelae (i.e. airway obstruction, severe sepsis, septic shock)IV (a or b depending on organ dysfunction
Bleeding/haematomaHaematoma not requiring drainage or suitable for simple aspiration with a needle (not radiologically guided)I
Need for blood transfusionII
Requiring drainage (not under GA). Includes radiologically guided aspiration/drainageIIIa
Requiring drainage or return to theatre for haemostasis (under GA)IIIb
Haematoma/haemorrhage sufficiently large to obstruct airway or cause hypovolaemic shockIV (a or b depending on organ dysfunction)
Chyle leakLow output leak (< 500 ml/24 h) suitable for low-fat diet and compression onlyI
Requirement for pharmacological management including total parenteral nutritionII
Radiologically guided occlusionIIIa
Return to theatre for the procedure under GAIIIb
Evidence of end-organ dysfunctionIV (a or b depending on organ dysfunction)
Wound breakdownSuperficial skin dehiscence (platysma layer intact) managed with dressingsI
Small fistula managed by an enteral tube or parenteral nutrition onlyII
Deep dehiscence (through platysma layer) or fistula managed with procedure not under GAIIIa
Deep dehiscence (through platysma layer) or fistula managed with the procedure under GAIIIb
Evidence of end-organ dysfunctionIV (a or b depending on organ dysfunction)
Seroma/sialoceleSmall collection not requiring drainage or suitable for aspiration with a needle (not radiologically guided)I
Salivary fistula managed medically (e.g. anticholinergic)II
Requiring drainage (not under GA). Includes radiologically guided aspiration/drainageIIIa
Requiring re-exploration and/or drainage (under GA)IIIb
Large collection obstructing airwayIVa
HypersensitivityMild reaction not requiring treatmentI
Mild/moderate/severe reaction treated with medication (e.g. antihistamine and/or steroid and/or adrenaline)II
Anaphylactic shockIV (a or b depending on organ dysfunction)
Air embolismBy definition clinically evident air embolism results in cardiorespiratory dysfunctionIVb
Pneumothorax/haemothoraxSmall pneumothorax managed without a chest drainI
Pneumothorax/Haemothorax without respiratory failure requiring chest drainIIIa
Evidence of respiratory failure or any other organ dysfunctionIV (a or b depending on organ dysfunction)
Pulmonary embolismSmall PE without evidence of respiratory failure managed with anticoagulation onlyII
Evidence of respiratory failure or any other organ dysfunctionIV (a or b depending on organ dysfunction)
Deep vein thrombosisManaged with anticoagulation onlyII
Need for endovascular intervention including filters not under GAIIIa
Need for endovascular intervention or surgical thrombectomy under GAIIIb
Lower respiratory tract infection (including aspiration)Managed with physiotherapy onlyI
Managed with antibioticsII
Evidence of respiratory failure or any other organ dysfunctionIV (a or b depending on organ dysfunction)
  1. GA general anaesthesia