Secondary outcome measures | |
---|---|
CPET | Change in VO2 peak (ml/min/kg), change in VO2 at AT (ml/min/kg) and change in FEV1 prior and post intervention |
Sarcopenia | Change in amount of L3 level skeletal muscle area determined on CT scan by methodology described by Perthen et al. [21], change in fat composition and volume measured by CT scan and change in grip strength pre and post intervention |
Exercise intervention | Change of step count throughout the intervention |
Oncological treatment | Number of patients with dose reductions or who terminate chemotherapy early, percentage of planned chemotherapy delivered, admissions to hospital with chemotherapy induced toxicity |
Quality of life | Change of score on validated quality of life questionnaires QLQ-C30 and QLQ-OG25 pre and post intervention |
Acceptability | Qualitative evidence generated from focus group discussions with participants |