Table 1 Summary of inputs used in model
Variable | Estimates (credible interval) | Distribution | n | Source/assumption |
|---|---|---|---|---|
Relative risk (regraft) [low-friction vs. standard] | 0.574 (0.52, 0.63) | Lognormal (− 0.56,0.61) | 221 | Before and after comparison—Silkie feasibility study |
P (regraft) low-friction | 0.038 (0.013, 0.077) | Beta (4.96,125.04) | 90 | Prospective data collection—Silkie feasibility study |
Intervention cost, £ | 115 | Deterministic | 131 | Estimate based on unit costing approach |
Cost (re-graft), £ | 19,321 (9092, 36,251) | Lognormal (9.81, 0.35) | 131 | “” |
Cost (no regraft), £ | 9908 (8319, 11,705) | Lognormal (9.20, 0.09)) | 131 | “” |
Utility post surgery | 0.353 (0.0056, 0.91) | Beta (0.77,1.41) | 40 | Prospective data collection—Silkie feasibility study |
Utility no graft loss | 0.508 (0.11, 0.90) | Beta (2.26, 2.19) | 27 | Prospective data collection—Silkie feasibility study |
Utility graft loss | 0.627 (0.57, 0.68) | Beta (179.95, 106.82) | 2 | |
Discount rate | 0.035 (−) | Deterministic | n/a | NICE methods of technology appraisal (2013) |