Table 2 Schedule of enrolment and assessments

Week

− 1

0

13

37

Visit number

1

2

3

4

Inclusion/exclusion criteria

X

X

X

X

Informed consent

X

Medical history

X

Physical examination

X

X

X

Exercise stress test/cardiac and vascular function

X

X

X

Intake 24

X

X

X

Physical activity

X

X

X

Stool/urine sample

X

X

X

Fasting blood sample

X

X

X

Oral glucose tolerance test

X

X

X

Skin swab

X

X

X

Body composition/waist:hip

X

X

X