Table 1 Schedule of trial assessments

Visit number

1

2

3

4

5

6

7

8

9

10

11

Time-point of visit

T-1 to 4 weeks

T0

T1

T-21

T22-T104

T83

T84

T[97-104]

T104

T164

T165

T185

Written informed consent

X

HADS

X

WASI

X

Blood tests (liver function, electrolytes)

X

ECG (where indicated)

X

MRI Safety Questionnaire

X

X

Issue of seizure diary

X

Structural MRI

X

X

Review of seizure frequency

X

X

X

X

X

X

X

X

X

QOLIE-31

X

X

X

Written Cognitive Assessments

X

Virtual Water Maze Task

X

X

X

X

X

X

X

X

X

Pattern separation task

X

X

X

Word Lists

X

X

X

X

X

X

X

X

X

Medical Outcomes Sleep Survey

X

X

X

Issue of SenseCam

X

X

X

Testing of SenseCam

X

X

X

X

X

X

X

X

X