Table 3 Data generated by proposed outcome measures at baseline and follow-up

STOPP mean (per patient) (range) SD^#

Median (IQR)

3.27 (0–7) 1.96

3.0 (2.0–4.25)

2.54 (0–5) 1.24,

2.0 (2.0–3.25)

START mean (per patient) (range) SD^#

Median (IQR)

2.35 (0–6)1.42

2 (1–3)

2.05 (0–6) 1.55

2.0 (1.0–3.0)

*Falls in past 3 months (total number)

12

10

Falls in past 3 months (number of patients falling)

9/40 (20%)

7/40 (17.5%)

Falls per person (mean (range) SD)

Median (IQR)

0.33 (0–3) 0.694

0.0 (0–0)

0.25 (0–2) 0.588

0.0 (0–0)

Barthel mean (range) SD

Median (IQR)

6.53 (0–17) 5.50

6.5 (1–9)

6.38 (0–19) 5.51

6.0 (1.0–10.0)

***MMSE mean (range) SD

Median (IQR)

Number

20.13 (9–30) 7.03

21.0 (14.25–25.5)

(n = 16)

20.79 (11–29) 5.90

20.5 (15–26)

(n = 14)

Drug burden index (DBI) score 0 (n (%))

14 (35%)

14 (35%)

**Drug burden index (DBI) N score > 0 (n (%))

Mean (range) SD

Median (IQR)

26 (65%)

1.11 (0.14–3.37) 0.74

1.035 (0.5–1.5)

26 (65%)

0.93 (0.14–3.34) 0.67

0.76 (0.5–1.17

Number of medicines per patient mean (range) SD)

Median (IQR) (includes topical preparations)

9.3 (1–26) 5.9

8.5 (6–12)

8.7 (0–31) 6.0

8 (5–10)

Total Qualidem mean, (range) SD,

Median, (IQR)

93 (67–130) 15.55

91.0 (79.25–101.5)

77.85 (31–109) 18.32

79.0 (71.0–92.5)

 a. Care relationship (mean (range) SD,

Median (IQR)

15.33 (10–23) 3.53

14.0 (12.25–18.0)

15.83 (4–21) 5.00

16.0 (13.0–20.0)

 b. Positive Affect mean (range) SD

Median (IQR)

14.33 (6–24) 5.50

14.5 (9.0–18.75)

12.43 (2–18) 4.33

14.0 (8.5–16.0)

 c. Negative Affect mean (range) SD

Median (IQR)

8.25 (3–12) 2.25

9.0 (6.0–10.0)

5.35 (0–9) 2.28

5.0 (4.0–7.0)

 d. Restless/tense behaviour mean (range) SD

Median (IQR)

8.48 (3–12) 2.59

9.0 (6.25–10.0)

5.13 (0–9) 2.41

5.0 (4.0–7.0)

 e. Positive self-image mean (range) SD

Median (IQR)

7.88 (3–11) 1.88

8.0 (6.0–9.0)

6.23 (0–9) 2.24

6.0 (4.25–8.75)

 f. Social Relations mean (range) SD

Median (IQR)

12.03 (7–22) 3.68

11.0 (10.0–13.0)

11.13 (1–18) 4.79

10.5 (8.25–15.75)

 g. Social Isolation (mean (range) SD

Median (IQR)

6.00 (3–11) 1.45

6.0 (5.0–7.0)

4.60 (10–9) 1.99

5.0 (4.0–6.0)

 h. Feeling at home mean (range) SD

Median (IQR)

8.88 (6–14) 2.22

8.0 (7.0–11.0)

9.68 (1–12) 2.74

11.0 (8.0–12.0)

†EQ 5D-5 L (self)

(Mean (range) SD) median (IQR)

N

0.449 (−0.281–0.951) 0.335

0.379 (0.279–0.719)

n = 16

0.572 (0.027–1.000) 0.327

0.585 (0.34–0.77)

n = 13

†EQ 5D-5 L (proxy) (mean (range) SD)

Median (IQR)

N

0.434 (−0.027–0.896) 0.229

0.356 (0.267–0.664)

n = 39

0.406 (−0.019–0.887) 0.236

0.341 (0.206–0.581)

n = 38

†EQ 5D-5 L Baseline VAS (self) (mean (range) SD)

Median (IQR)

N

57.5 (0–100) 31.9

67.5 (32.5–75)

n = 14

62.9 (10–99) 30.2

75 (30–85)

n = 11

†EQ 5D-5 L Baseline VAS (proxy) (mean (range) SD)

Median (IQR)

N

51.6 (2–99) 23.9

57.5 (38.75–66.25)

n = 38

50.2 (2–90) 27.3

50 (30–70)

n = 37

Adverse drug events related to intervention (ADEs) in past three months

0/40 (0%)

0/40 (0%)