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Table 3 Published experience with esmolol infusion in septic shock

From: Esmolol infusion in patients with septic shock and tachycardia: a prospective, single-arm, feasibility study

Hospital/country

Patients receiving esmolol (n)

Wait 24 hb

Peak infusion rates (μg/kg/min)a

Esmolol mortality (%)

Use of non-adrenergic inotropes

RCTd

Intermountain/USA

7

No

50 (25–50)

0

No

No

La Sapienza/Italy [23]

77

Yes

22 (11–66)

49

Yes

Yes

La Sapienza/Italy [22]

26

Yes

55 (22–233)

NAc

Likelyc

No

La Sapienza/Italy [44]

45

Yes

NAc

51

Likelyc

No

Prague/Czech Rep [49]

10

No

61 ± 20

10

No

No

Peking Union/China [54]

63

No

25 ± 20

8

No

No

Jiangxi/China [53]

30

No

NAc

40

Yes

Yes

  1. aWe assumed 75 kg body mass where unindexed rates provided
  2. bPatients were enrolled only > 24 h after onset of septic shock
  3. cAuthors did not reply to email request for this data
  4. dUtilized a randomized controlled design