Table 3 Univariate and multivariable analysis of factors associated with reported items

 • 1990–2006

 • 2007–2016

0.99 (0.91; 1.08)

0.86

1.07 (0.91; 1.13)

0.74

 • Pharmacological

 • Non-pharmacological

0.93 (0.86; 1.01);

0.07

0.88 (0.81; 0.97)

0.01

 • Structured

 • Unstructured

1.11 (0.99; 1.24)

0.08

1.10 (0.99; 1.23)

0.05

 • Yes

 • No

1.07 (0.98; 1.16)

0.12

1.10 (0.99; 1.23)

0.06

 • Single

 • Multiple

1.08 (0.97; 1.22)

0.14

1.02 (0.92; 1.15)

0.62

Study duration*

1.03 (1.01; 1.06)

0.02

Sample size*

1.01 (0.96; 1.07)

0.63