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Table 3 Results of participant-rated and carer-rated outcomes

From: Lee Silverman Voice Treatment versus standard speech and language therapy versus control in Parkinson’s disease: a pilot randomised controlled trial (PD COMM pilot)

  Baseline 3 Months   
  LSVT NHS Control LSVT NHS Control LSVT vs. control NHS vs. control
VHI total score N = 26
42 (20.2)
N = 28
42 (25.5)
N = 26
42 (21.0)
N = 22
33 (22.4)
N = 22
36 (21.2)
N = 28
46 (25.1)
− 12.5 (− 26.2 to 1.2) − 9.8 (− 23.2 to 3.7)
PDQ-39 communication domain N = 29
35 (23.3)
N = 30
33 (21.5)
N = 29
33 (19.5)
N = 26
27 (22.9)
N = 27
30 (19.4)
N = 29
35 (24.0)
− 7.5 (− 20.3 to 5.2) − 5.0 (− 16.7 to 6.8)
PDQ-39 summary index N = 29
32 (15.5)
N = 30
28 (13.8)
N = 29
26 (14.1)
N = 26
29 (17.5)
N = 27
27 (13.8)
N = 29
29 (16.3)
− 0.2 (− 9.3 to 9.0) − 2.1 (− 10.2 to 6.0)
V-RQoL N = 27
20 (8.9)
N = 25
20 (8.3)
N = 25
21 (7.1)
N = 21
18 (7.8)
N = 24
19 (5.6)
N = 28
22 (8.0)
− 3.5 (− 8.1 to 1.1) − 3.2 (− 7.1 to 0.7)
LwD N = 27
28 (16.2)
N = 27
32 (21.9)
N = 26
27 (20.7)
N = 25
24 (21.6)
N = 24
28 (17.1)
N = 25
29 (20.4)
− 5.6 (− 17.6 to 6.3) − 1.9 (− 12.8 to 8.9)
EQ-5D QoL score N = 29
0.59 (0.30)
N = 30
0.64 (0.23)
N = 29
0.72 (0.18)
N = 26
0.60 (0.27)
N = 27
0.70 (0.20)
N = 28
0.60 (0.29)
0.004 (− 0.15 to 0.16) 0.11 (− 0.03 to 0.25)
PDQ-Carer summary index N = 11
27 (19.7)
N = 11
26 (20.9)
N = 3
15 (18.2)
N = 11
32 (22.9)
N = 7
21 (13.4)
N = 4
18 (17.8)
15.8 (− 15.7 to 47.3) 5.9 (− 19.1 to 30.9)
  1. Mean difference (95% CI) for comparisons
  2. VHI ranges from 0 to 120; PDQ-39 ranges from 0 to 100; V-RQoL ranges from 10 to 50; LwD ranges from 0 to 90; PDQ-Carer ranges from 0 to 100, where low score is good. Negative difference favours treatment
  3. EQ-5D ranges from − 0.59 to 1, where high score is good. Positive difference favours treatment