Skip to main content

Table 3 Results of participant-rated and carer-rated outcomes

From: Lee Silverman Voice Treatment versus standard speech and language therapy versus control in Parkinson’s disease: a pilot randomised controlled trial (PD COMM pilot)

 

Baseline

3 Months

  
 

LSVT

NHS

Control

LSVT

NHS

Control

LSVT vs. control

NHS vs. control

VHI total score

N = 26

42 (20.2)

N = 28

42 (25.5)

N = 26

42 (21.0)

N = 22

33 (22.4)

N = 22

36 (21.2)

N = 28

46 (25.1)

− 12.5 (− 26.2 to 1.2)

− 9.8 (− 23.2 to 3.7)

PDQ-39 communication domain

N = 29

35 (23.3)

N = 30

33 (21.5)

N = 29

33 (19.5)

N = 26

27 (22.9)

N = 27

30 (19.4)

N = 29

35 (24.0)

− 7.5 (− 20.3 to 5.2)

− 5.0 (− 16.7 to 6.8)

PDQ-39 summary index

N = 29

32 (15.5)

N = 30

28 (13.8)

N = 29

26 (14.1)

N = 26

29 (17.5)

N = 27

27 (13.8)

N = 29

29 (16.3)

− 0.2 (− 9.3 to 9.0)

− 2.1 (− 10.2 to 6.0)

V-RQoL

N = 27

20 (8.9)

N = 25

20 (8.3)

N = 25

21 (7.1)

N = 21

18 (7.8)

N = 24

19 (5.6)

N = 28

22 (8.0)

− 3.5 (− 8.1 to 1.1)

− 3.2 (− 7.1 to 0.7)

LwD

N = 27

28 (16.2)

N = 27

32 (21.9)

N = 26

27 (20.7)

N = 25

24 (21.6)

N = 24

28 (17.1)

N = 25

29 (20.4)

− 5.6 (− 17.6 to 6.3)

− 1.9 (− 12.8 to 8.9)

EQ-5D QoL score

N = 29

0.59 (0.30)

N = 30

0.64 (0.23)

N = 29

0.72 (0.18)

N = 26

0.60 (0.27)

N = 27

0.70 (0.20)

N = 28

0.60 (0.29)

0.004 (− 0.15 to 0.16)

0.11 (− 0.03 to 0.25)

PDQ-Carer summary index

N = 11

27 (19.7)

N = 11

26 (20.9)

N = 3

15 (18.2)

N = 11

32 (22.9)

N = 7

21 (13.4)

N = 4

18 (17.8)

15.8 (− 15.7 to 47.3)

5.9 (− 19.1 to 30.9)

  1. Mean difference (95% CI) for comparisons
  2. VHI ranges from 0 to 120; PDQ-39 ranges from 0 to 100; V-RQoL ranges from 10 to 50; LwD ranges from 0 to 90; PDQ-Carer ranges from 0 to 100, where low score is good. Negative difference favours treatment
  3. EQ-5D ranges from − 0.59 to 1, where high score is good. Positive difference favours treatment