Table 3 Genetic knowledge responses
From: Development of a communication aid for explaining hypertrophic cardiomyopathy genetic test results
Knowledge item | Answered correctly, n (%) |
|---|---|
1. 50% of your genetic information is passed down from your mother (true) | 8 (67) |
2. 25% of your genetic information passed down from your father (false) | 7 (58) |
3. Each daughter and son has the same chance of developing HCM if one parent has HCM (true) | 10 (83) |
4. Genetic testing is the only way of finding out if someone has HCM (false) | 10 (83) |
5. An inherited HCM pathogenic variant is present in the DNA in every cell of the body (true) | 5 (42) |
6. There is more than one gene in humans, which if damaged, can cause HCM (true) | 7 (58) |
7. If a parent has an HCM pathogenic variant, each child has a 50% chance of inheriting it (true) | 11 (92) |
8. An individual who has a sibling with a HCM pathogenic variant has a 25% of also having the same variant (false) | 5 (42) |
9. If a person with HCM has an indeterminate genetic test result this means HCM is not inherited in their family (false) | 8 (67) |
10. A VUS may or may not be significant. More evidence and information is needed to know if this is important (true) | 10 (83) |