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Table 1 NEC prophylaxis regimens

From: Changes of intestinal microbiota composition and diversity in very low birth weight infants related to strategies of NEC prophylaxis: protocol for an observational multicentre pilot study

  NICU Graz NICU Klagenfurt NICU Leoben
Probiotics Lactobacillus rhamnosus 1 g = 1 × 109 CFU/d p.o. split into 2 doses Bifidobacterium infantis 2x109CFU/d and Lactobacillus acidophilus 2x109CFU/d in combination p.o. None
Antibiotics Gentamycin 7 mg/kg every 12 h p.o. None Gentamycin 7 mg/kg every 12 h p.o.
Antifungal agents Nystatin 10.000 U/kg every 6 h p.o. Fluconazol 6 mg/kg i.v. every 72 h (< 1000 g birth weight) Nystatin 10.000 U/kg every 6 h p.o.
Feeding Pooled or pasteurised BM; subsequent transition to mothers’ BM or preterm formula (hydrolyzed in case of birth weight < 1000 g) Pasteurised BM (no pooled BM) or preterm formula Pooled or pasteurised BM; subsequent transition to mothers’ BM or preterm formula (hydrolyzed in case of birth weight < 1000 g)
  1. Legend: Table 1 displays NEC prophylaxis regimens used at the participating study centres at the Medical University Graz, General Hospital of Klagenfurt and General Hospital of Leoben
  2. BM breast milk, p.o. per os, CFU colony forming unit, U units, d day, g gram, kg kilogramme, mg milligramme