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Table 1 NEC prophylaxis regimens

From: Changes of intestinal microbiota composition and diversity in very low birth weight infants related to strategies of NEC prophylaxis: protocol for an observational multicentre pilot study

 

NICU Graz

NICU Klagenfurt

NICU Leoben

Probiotics

Lactobacillus rhamnosus 1 g = 1 × 109 CFU/d p.o. split into 2 doses

Bifidobacterium infantis 2x109CFU/d and Lactobacillus acidophilus 2x109CFU/d in combination p.o.

None

Antibiotics

Gentamycin 7 mg/kg every 12 h p.o.

None

Gentamycin 7 mg/kg every 12 h p.o.

Antifungal agents

Nystatin 10.000 U/kg every 6 h p.o.

Fluconazol 6 mg/kg i.v. every 72 h (< 1000 g birth weight)

Nystatin 10.000 U/kg every 6 h p.o.

Feeding

Pooled or pasteurised BM; subsequent transition to mothers’ BM or preterm formula (hydrolyzed in case of birth weight < 1000 g)

Pasteurised BM (no pooled BM) or preterm formula

Pooled or pasteurised BM; subsequent transition to mothers’ BM or preterm formula (hydrolyzed in case of birth weight < 1000 g)

  1. Legend: Table 1 displays NEC prophylaxis regimens used at the participating study centres at the Medical University Graz, General Hospital of Klagenfurt and General Hospital of Leoben
  2. BM breast milk, p.o. per os, CFU colony forming unit, U units, d day, g gram, kg kilogramme, mg milligramme