Skip to main content

Table 4 Levels of markers of inflammation, stress, and other hormones associated with breast cancer risk in breast cancer survivors over time (n = 10 per group)

From: Effects of a parallel-arm randomized controlled weight loss pilot study on biological and psychosocial parameters of overweight and obese breast cancer survivors

 

Week 0

Week 6

Week 12

Week 18

Leptin (ng/mL)

 CR

47 (34.8, 59.3)

21.5 (9.3, 33.8)

19 (6.7, 31.2)

26.2 (14, 38.5)

 WM

53.8 (41.5, 66)

37.3 (25, 49.5)

36.8 (24.5, 49)

38.2 (26, 50.5)

Adiponectin (μg/mL)

 CR

12.8 (9.3, 16.2)

9.6 (6.2, 13)

11.1 (7.7, 14.5)

13.8 (10.4, 17.2)

 WM

7.7 (4.3, 11.1)

6.9 (3.5, 10.3)

7.9 (4.5, 11.3)

8.3 (4.9, 11.7)

CRP (mg/L)

 CR

6 (2.1, 9.8)

4.3 (0.4, 8.1)

3.2 (0, 7.1)

3.8 (0, 7.7)

 WM

5.2 (1.3, 9)

4.4 (0.6, 8.2)

7.4 (3.6, 11.3)

5.9 (2, 9.7)

Interleukin-6 (pg/mL)

 CR

2.7 (1.8, 3.6)

2 (1.1, 2.9)

2.2 (1.3, 3.1)

2.4 (1.6, 3.3)

 WM

2.8 (1.9, 3.7)

2.4 (1.5, 3.3)

3.3 (2.4, 4.2)

2.7 (1.8, 3.6)

F2-isoprostanes (ng/mL)

 CR

71.5 (52.5, 90.4)

–

50 (31.1, 68.9)

52.9 (33.9, 71.8)

 WM

81 (62, 100)

–

62 (43.1, 81)

64.9 (46, 83.9)

Cortisol (ng/mL)

 CR

26.4 (18.3, 34.6)

21.2 (13.1, 29.4)

27.1 (19, 35.3)

23.1 (14.9, 31.3)

 WM

40.3 (32.1, 48.5)

28.3 (20.1, 36.5)

36.1 (27.9, 44.3)

37 (28.8, 45.1)

6-Sulfatoxymelatonin (ng/mg cr)

 CR

8.1 (3, 13.3)

8.6 (3.5, 13.8)

5.8 (0.1, 11.6)

10 (4.9, 15.2)

 WM

15.8 (10.7, 21)

13.1 (7.7, 18.5)

11.6 (6.4, 16.7)

16.9 (11.8, 22.1)

  1. Values displayed as mean (95% confidence interval)
  2. Abbreviations: CR calorie restricted diet plus exercise group, WM weight management counseling group, CRP C-reactive protein