• Small dose of vasoactive agents (e.g. 0.1–0.2 mcg/kg/min noradrenaline or equivalent) required for haemodynamic stability |  |
• Mechanically ventilated with FiO2 >0.6 and/or PEEP >10 cmH2O |  |
• Poor tolerance of endotracheal tube |  |
• Open abdomen or high risk for dehiscence—liaise with surgical team prior to mobilising |  |
• Haemofiltration via a femoral line |  |