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Table 2 Comparison of mean and median monthly reduction in MBL for the group between the pre-treatment phase and the treatment phase

From: Potentially effective therapy of heavy menstrual bleeding with an oestradiol-nomegestrol acetate oral contraceptive: a pilot study

Variable

Number

Mean (mL)

Std Devn (mL)

Median (mL)

Minimum (mL)

Maximum (mL)

Mean (mL) before treatment (cycles 1, 2 and 3)

10

128.4

52.0

128.4

72.5

242.1

Mean (mL) on treatment (cycles 5, 6 and 7)

10

26.6

16.3

22.9

0.0

56.8

Difference in means (before treatment compared to on-COC)

10

101.9

49.3

97.9

39.0

185.2

Percent reduction

10

76.9

13.8

79.0

53.7

100.0

  1. Ninety-five percent confidence interval for difference in means (66.6, 137.1), P = 0.0001 (paired t test), P = 0.002 (signed-rank test). Ninety-five percent confidence interval for percent reduction (67.0, 86.8), P < 0.0001 (one sample t test), P = 0.002 (signed-rank test)