Skip to main content

Advertisement

Table 2 Primary and secondary outcomes with data sources to investigate the impact of diagnostic and treatment procedures in patients with suspected UTI in human and veterinary primary care practices in Denmark

From: Exploring the feasibility and synergistic value of the One Health approach in clinical research: protocol for a prospective observational study of diagnostic pathways in human and canine patients with suspected urinary tract infection

General practice Veterinary practice
Primary outcome Source of data Primary outcome Source of data
Proportion of (i) appropriate decisions to treat with antibiotics and (ii) appropriate choices of antibiotic for each diagnostic path Case report form Proportion of (i) appropriate decisions to treat with antibiotics and (ii) appropriate choices of antibiotic for each diagnostic path Case report form
Difference in the percentage of patients with appropriate antibiotic treatment when comparing diagnostic pathways during the consultation and diagnostic pathways after the consultation Culture report from SSIa Difference in the percentage of patients with appropriate antibiotic treatment when comparing diagnostic pathways during the consultation and diagnostic pathways after the consultation Culture report from SVDa
Secondary outcomes   Secondary outcomes  
Validity of each diagnostic path Case report form Validity of each diagnostic path Case report form
Culture report from SSI Culture report from SVD
Number of days until clinical cure (i.e., first day without symptoms from the urinary tract) Symptom diary Number of days until clinical cure (i.e., first day without clinical signs from the urinary tract Symptom diary
Prevalence of uro-pathogens Culture report from SSI Prevalence of uro-pathogens Culture report from SVD
Susceptibility patterns for each bacterial strain Culture report from SSI Susceptibility patterns for each bacterial strain Culture report from SVD
Prevalence of ESBL-resistant E. coli Culture report from SSI Prevalence of multi-resistant bacterial strains Culture report from SVD
Risk factors for harboring ESBL-resistant E. coli Culture report from SSI n.a. n.a.
Patient questionnaire
  1. SSI Statens Serum Institute, SVD SUND VET DIAGNOSTIK, ESBL extended spectrum beta-lactamase, n.a. not available
  2. aReference laboratories