Table 2 Primary and secondary outcomes with data sources to investigate the impact of diagnostic and treatment procedures in patients with suspected UTI in human and veterinary primary care practices in Denmark
General practice | Veterinary practice | ||
|---|---|---|---|
Primary outcome | Source of data | Primary outcome | Source of data |
Proportion of (i) appropriate decisions to treat with antibiotics and (ii) appropriate choices of antibiotic for each diagnostic path | Case report form | Proportion of (i) appropriate decisions to treat with antibiotics and (ii) appropriate choices of antibiotic for each diagnostic path | Case report form |
Difference in the percentage of patients with appropriate antibiotic treatment when comparing diagnostic pathways during the consultation and diagnostic pathways after the consultation | Culture report from SSIa | Difference in the percentage of patients with appropriate antibiotic treatment when comparing diagnostic pathways during the consultation and diagnostic pathways after the consultation | Culture report from SVDa |
Secondary outcomes | Secondary outcomes | ||
Validity of each diagnostic path | Case report form | Validity of each diagnostic path | Case report form |
Culture report from SSI | Culture report from SVD | ||
Number of days until clinical cure (i.e., first day without symptoms from the urinary tract) | Symptom diary | Number of days until clinical cure (i.e., first day without clinical signs from the urinary tract | Symptom diary |
Prevalence of uro-pathogens | Culture report from SSI | Prevalence of uro-pathogens | Culture report from SVD |
Susceptibility patterns for each bacterial strain | Culture report from SSI | Susceptibility patterns for each bacterial strain | Culture report from SVD |
Prevalence of ESBL-resistant E. coli | Culture report from SSI | Prevalence of multi-resistant bacterial strains | Culture report from SVD |
Risk factors for harboring ESBL-resistant E. coli | Culture report from SSI | n.a. | n.a. |
Patient questionnaire | |||